Alzheimer’s disease is physiologically characterized by β and tau amyloid- related peptides aggregation which precipitates as fibrils in the brain (hippocampus and prefrontal cortex) and affects its correct functioning.
According to the publication, this two step study has highlighted that :
On the one hand (in vitro) :Oligopin® prevents the generation of aggregation by stopping crosslinking of Aβ and tau amyloid- related soluble peptides
On the other hand (in vivo)Oligopin® metabolites ( methylated and glucuronide forms of catechin and epicatechin ) can cross the blood brain barrier and be active in the brain.
The authors of the study recommend considering Oligopin® as an interesting option to further investigate prevention and treatment of Alzheimer condition
Journal of Alzheimer’s Disease 73 (2020) 1597–1606 DOI 10.3233/JAD-190543 IOS Press
OLIGOPIN®* is a natural pine bark extract, concentrated in OPC ( Procyanidins )
For more information, please visit www.theoriginalpinebarkextract.com or contact us : info@purextract.fr